THE SCIENCE BEHIND HYPERBARIC OXYGEN THERAPY (HBOT)
At Renume Wellness, we believe in therapies backed by science. Hyperbaric Oxygen Therapy (HBOT) has been extensively studied worldwide for its physiological effects on the body. Below, we outline some of the key areas of research that contribute to HBOT’s potential applications.
How HBOT Works at a Cellular Level
Hyperbaric oxygen involves breathing 100% oxygen in a pressurised environment, significantly increasing the amount of oxygen dissolved in plasma. This heightened oxygen delivery has been shown to:
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Enhance mitochondrial function, supporting cellular energy production (ATP).
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Promote angiogenesis (new blood vessel formation) in oxygen-deprived tissues.
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Mobilise stem cells from bone marrow to aid in tissue regeneration.
Areas of Active Research and Application
Tissue repair & wound healing
Studies show HBOT can stimulate fibroblast activity, collagen synthesis, and improve healing of chronic wounds.
Neurological health
Evidence suggests HBOT may enhance neuroplasticity, supporting recovery in brain injuries and strokes.
Inflammation and oxidative stress
Research indicates HBOT modulates inflammatory markers and supports antioxidant enzyme systems.
Radiation tissue injury
HBOT is recognised for treating soft tissue and bone necrosis after radiotherapy.
Recognised Medical Indications
Globally, HBOT is part of mainstream medical practice for conditions such as:
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Decompression sickness
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Carbon monoxide poisoning
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Gas embolism
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Chronic bone infections
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Compromised skin grafts/flaps
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These uses are supported by guidelines from bodies such as the Undersea and Hyperbaric Medical Society (UHMS).
Further Reading
